4-TRIFLUOROMETHOXY BENZOIC ACID, [CARBOXYL-14C] - Names and Identifiers
4-TRIFLUOROMETHOXY BENZOIC ACID, [CARBOXYL-14C] - Physico-chemical Properties
Molecular Formula | C8H5F3O3
|
Molar Mass | 208.14 |
4-TRIFLUOROMETHOXY BENZOIC ACID, [CARBOXYL-14C] - Introduction
4-Trifluoromethoxybenzoic acid is an organic compound with the chemical formula C8H5F3O3. The following is a description of the properties, uses, preparation and safety information of 4-trifluoromethoxybenzoic acid:
Nature:
-Appearance: 4-Trifluoromethoxybenzoic acid is a colorless or slightly yellow crystalline solid.
-Melting point: about 160-161 ° C.
-Boiling point: About 234.6 ° C.
-Solubility: 4-trifluoromethoxybenzoic acid is not easy to dissolve in water, but can be dissolved in organic solvents.
Use:
-4-Trifluoromethoxybenzoic acid can be used in organic synthesis and pharmaceutical research.
-It can be used as substrates and reagents in organic synthesis, and participate in the preparation of organic compounds such as esters, ketones and ethers.
-In drug research, it can be used to label the carboxyl groups in drug molecules for drug metabolism and Analysis Research.
Preparation Method:
The preparation of -4-trifluoromethoxybenzoic acid can be obtained by The trifluoromethoxylation reaction of benzoic acid.
-Reaction 1: React benzoic acid with trifluoromethyl alcohol in the presence of an acidic catalyst (such as trifluoroacetic acid) and heat to an appropriate temperature to obtain 4-trifluoromethoxybenzoic acid.
Safety Information:
- 4-trifluoromethoxy benzoic acid is an organic compound, which is dangerous to human body.
-use should take appropriate protective measures, such as wearing protective glasses, respirators.
-Avoid contact with skin and eyes, such as rinse with plenty of water immediately after contact.
-When used in the laboratory, care should be taken to prevent contact with fire sources.
-When storing, it should be stored in a dry, ventilated and dark place, away from fire and flammable materials.
Last Update:2024-04-09 02:00:38